If you’ve looked into MK-677 or Ibutamoren you’ve probably heard of its effects on sleep quality. Most effects are very positive. However, it can cause feelings of extreme tiredness and lethargy in many.

Does MK-677 Make You Tired?

Mk-677 acts on ghrelin receptors which will greatly improve sleep quality. At the same time, it can cause lethargy in many users. This can be combated by taking smaller doses, taking it at different times during the day, or ultimately just not taking it.

Disclaimer: This compound is not permitted for human consumption as it’s considered a compound of an Investigational New Drug. The use of MK-677 is approved for research purposes. Therefore, it is legal to obtain it or any other SARMs sold under the label, research chemicals.

It has not been tested on humans and should not be considered safe to consume.

What Is MK677 Or Ibutamoren?

MK-677 is an orally active growth hormone secretagogue and is not actually considered a sarm even though it is often grouped together with other sarms.

Growth hormone secretagogues are peptides or nonpeptidic agents that release GH from the pituitary. This will increase growth hormone levels in the body.

Growth hormone is an anabolic hormone that is responsible for promoting muscle growth, weight gain, and nitrogen retention in the body.

In both children and adults, growth hormone helps control the body’s metabolism.

Mk-677 binds to ghrelin receptors in the brain to increase growth hormone levels. Ghrelin receptors are found in the brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

The main benefit of MK-677 is that it increases both growth hormone levels and Insulin-Like Growth Factor levels in the body.

Both of these hormones help increase lean muscle mass, recovery, strength and performance. They have also been shown to play an essential role in regulation of muscle tissue development and maintenance.

MK-677 will improve sleep quality by increasing REM sleep by up to 50%. REM sleep usually occurs about 90 minutes after we fall asleep and it is where brain activity increases, and dreaming is most present.

REM sleep is important for learning and memory and is a crucial part of sleep.

MK-677 also causes an increase in hunger. If you are having trouble putting on size, this can be beneficial for you.

However, if you’re not trying to eat a lot, consider taking your dosage at night to reduce feeling as hungry throughout the day.

Sleep Quality And Lethargy

How exactly does it improve your sleep quality?

Similar to how it builds muscle, by increasing the production of GH and IGF-1.

Why is sleep quality so important? I’m sure you’ve heard more than once how vital sleep is when trying to build muscle. That is because this when your muscles recover and grow.

When you workout in the gym, you are breaking down the muscles and then they will regrow larger and stronger while you sleep. Studies have shown that those who get 7-9 hours of sleep actually produce a lot more testosterone than those who get less than 7.

By increasing sleep quality, you are increasing the recovery and growth of your muscles.

By acting on the ghrelin receptors, MK-677 will most likely cause tiredness. Experiment with your dosage times as this should make a difference. Most people find that taking it sometime in the evening is best for reducing lethargy.

This can be caused by high prolactin levels which can suppress dopamine and basically sedate you. Supplementing with V6 may help balance prolactin levels.

Lowering your dosage may also be a good thing to try.

Consider using caffeine and supplements to fight lethargy. Here’s a great stim-free pre-workout that I would recommend for a great workout and for fighting lethargy.

If you have tried switching your dosage times and are still extremely tired, it may be best to completely quit taking the substance.

It’s also important to note that impure MK-677 may lead to more tiredness. That is why it is always important to find a trusted source that will be providing you with 100% pure MK-677.

Unfortunately, the lethargy does not seem to fade even if taking MK-677 for a long period. If you have tried all the above options, then your best bet is probably not to take it.


The benefits of Ibutamoren include muscle-building, a reduction in muscle-wasting, better bone density, improved sleep, and anti-aging properties. It can also benefit in treating growth hormone deficiencies.

How does it help with building muscle? Probably the main reason why most people take it is to put on muscle mass.

By stimulating growth hormone and IGF-1 in the body, which will increase muscle size and strength.

MK-677 has also been shown to reduce muscle wasting caused by a decline in protein intake. In studies, it has proven to reverse the effects of protein catabolism. Even if you are not eating adequate protein, it can stop muscles from getting weaker. Obviously this is not ideal and protein intake should be high while taking the substance for the most gains.

Growth hormone helps with repairing muscle tissue and other cells quickly, so you can expect quicker recovery after a tough workout.

You will have reduced soreness after a workout, and your muscles will rebuild quicker. This means that you can train them again sooner, leading to more gains.

MK-677 has also been known to increase fat loss. By increasing lean muscle mass, your body will actually burn more fat. The muscle provided by growth hormone is also lean mass, and will not add on body fat.

Safety And Dosage

Users usually take 20-30mg per day. This what is required to achieve the best results and minimal side effects. Anything above 30mg won’t produce any extra results and can be harmful.

It’s usually taken for cycles lasting 8-16 weeks. The effects take a while to occur so it’s better taken over a longer period. It should not be taken for longer than 6 months.

The half-life is 24 hours and can be taken once per day, orally.

It’s important to note that MK-677 does not have a lot of information and studies done on it yet. This means that there could be side effects that are not yet known.

Side Effects?

One of the facts that make MK-677 very tempting to take is that it does not suppress natural testosterone levels like steroids and SARMS do. This means you can take it without having to worry about a PCT or losing your gains after your cycle.

It also doesn’t seem to have many serious side effects. However, note that it has not been around long enough to have real studies done on it so some side effects may not be known yet.

Increased appetite may be a side effect for some if they are trying to lose weight. The lethargy mentioned in the article is another.

Joint and muscle pain have been reported by users along with headaches. This can also be because users are gaining muscle quicker and stacking on more weight in the gym. If their joints are not used to this added weight, it can lead to pain and possible injury.

Water retention or bloating is common when taking MK-677. To reduce this, keep your nutrition in check. Watch your fat and sodium intake.

High blood sugar levels have been noted when taking MK-677 so blood sugar should be watched while on it. Reduced insulin sensitivity also goes along with this.

Know that more severe side effects are usually only noticed when taking too high of a dose or when taking it for an extended period.

Let me know if you have any questions or comments and I’ll be sure to get back to you!

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